Resume. Up-to-date

Positions

2012 - 2017
Roche Tissue Dx
Tucson, AZ
Vice President, Platform Systems
Functional leader for engineering and software product development. I was also project lead for HE600 product and led a major change management effort with Accenture improving the SW development processes.

2009 - 2012
Novartis Dx
Emeryville, CA
Development Franchise Head
As a leader in blood screening for viral pathogens, the divisional strategy aimed to broaden the molecular Dx portfolio. I established and managed a multi-functional incubator to develop diagnostic solutions for hospital acquired infections. The technology commercialized as AXDX

2006 - 2009
Novartis Dx
Emeryville, CA
Senior Director, Instrument Systems
I directed team responsible for development, evaluation and acquisition of systems (instrumentation, software, disposables) for the diagnostic blood screening product choices. Procleix product line ( Panther and Tigris) are global market leader in high throughput molecular assays.

2004 - 2006
Nanomix, Inc.
Emeryville, CA
Vice President, R&D
Worked with president to raise a $16M C-round. Re-built the R&D team and expanded patent portfolio for carbon nanotube sensors. Launced first industrial sensor and initiated research for life science applications

1998 - 2004
Nanogen, Inc.
San Diego, CA
Vice President, Platform Systems
My team developed the first active CMOS chip-based platform for genetic analysis. This technology, invented at UCSD, was the predecessor of multiple gene-sequencing platforms that have revolutionized the understanding of genetics in medicine. Fundamental scientific challenges in linking the biology to the micro-electronics (permeation layer, packaging, field modeling) were solved in the Nanogen platform and were carried over in several subsequent product variants

Technical

System Architecture
100%
Design Control
95%
Software Development (Firmware - Cloud - Devops)
90%
Biomedical (Combination product/Assays/Pharma)
80%
Micro-Nano Fabrication
70%

Languages

English
Fluent
Dutch
Native
French
Advanced
German
Beginner

Additionally

  • requirements management
  • project & budget management
  • strong organizational skills
  • excellent interpersonal skills
  • configuration management
  • V&V
  • regulatory submissions
  • clinical trial planning
1996
University of California, San Diego
San Diego, CA
Executive Program
  • Organizational Structure
  • Strategy
  • Management and Leadership
1986 - 1987
University of California, Los Angeles
Los Angeles, CA
Post Doctoral, Respiratory Physiology
  • Ventilatory Parameter Estimation
  • Control of breathing modeling
  • Physiological Data Acquisition

1982 - 1987
University of California, Los Angeles
Los Angeles, CA
M.Sc & Ph.D. Electrical Engineering
  • Kalman Filtering
  • System Control
  • Stochastic Systems
  • Digital Communication

1976 - 1981
KU Leuven
Leuven, Belgium
B.Sc./M.Sc. Electrical Engineering
  • Mechanical/Power Systems
  • Computer Sciences
  • System Control Theory
  • Applied Mathematics-Chemistry-Physics
500+
engaged employees
7
new platforms
>15
patents
>50
publications

Chris Valcke is an extremely intelligent and creative R&D leader. He has a unique set of expertise across numerous technical disciplines, combined with good business sense and knowledge of regulatory affairs. Chris is also a gifted leader and manager of people and projects. I worked with Chris at both Nanomix and Nanogen. I would enjoy working with Chris again anytime and I give him my highest reccomendation.

David MacDonald

Chris is an outstanding Senior Leader who has that rare talent of motivating his people to want to do more for the organization. He is exceptionally smart, with remarkable skills in strategic decision-making and a solid product delivery record. At the same time, he is still able to maintain a genuine quality and connection with his people. I learned much from him in the near five years I worked within his organization. It would be a privilege to work for him again

Kayla Capps

As the medical expert of the team, I found that Chris excelled at assimilating my advice with those of the rest of the diverse team, ranging from the technical experts to business development, to drive towards clear development objectives. I enjoyed working under Chris and found him to be personable and friendly while also providing the necessary direction and support for me to establish my medical affairs role. He is always open to feedback and finds time to coach team members as needed.

Taylor Sandison, M.D.

Craig, ...Valcke, “Sensor having a thin-film inhibition layer”, US 9,291,613, Mar2016

Briman,...,Valcke, “Electrochemical nanosensors for biomolecule detection”, US 9,234,867, Jan 2016

Bradley,...Valcke, “Nano-electronic sensors for chemical and biological analytes, including capacitance and bio-membrane devices”, US 9,103,775, Aug 2015

Kanchan, …, Valcke, “Nanoelectronic electrochemical test device”, US 8,778,269, July 2014

Bryant, ...Valcke, “Sensor having a thin-film inhibition layer”, US 8,754,454, June 2014

Briman, Radkey, Tu, Valcke, “Electrochemical nanosensors for biomolecule detection”, US 8,425,745, April 2013

B. Keith, C. Valcke, “Nano-electronic sensors for chemical and biological analytes, including capacitance and bio-membrane devices”, US 8,154,093, 2012

M. Briman, C.Valcke, “Ammonia nanosensors, and environmental control system”, 8,152,991, 2012

K. Joshi, C. Valcke, “Nanoelectronic electrochemical test device”, 7,955,559, 2011

B. Craig, C. Valcke, “Sensor having a thin-film inhibition layer”, 7,948,041, 2011

B. Nadav, C. Valcke, “Nanoelectronic measurement system for physiologic gases and improved nanosensor for carbon dioxide”, 7,714,398, 2010.

C. Valcke, R. Hillman, W. Bochenko, “Method for closed-loop drug delivery”, US 5,733,259, 1998

R. Hillman, C. Valcke, “Feedback Controlled Drug Delivery System”, US 5,697,899, 1997

Weigel KM, Jones KL, Do JS, Witt JM, Chung JH, Valcke C, Cangelosi GA (2013). “Molecular viability testing of bacterial pathogens in a complex human sample matrix”, PLoS ONE, 8(1):e54886. PMC3554692 .

A. Star, G. Tu, J. Nieman, JC Gabriel, S. Joiner, C. Valcke, “Label-free detection of DNA hybridization using carbon nanotube network field-effect transistors”, PNAS, Jan 2006.

C. Cannon, J Dingemanse, K Kleinbloesem, K Curry, T. Jannett, C. P. Valcke “Automated Heparin-Delivery System to Control Activated Partial Thromboplastin Time : Evaluation in Normal Volunteers.”, Circulation, pg. 751-756, v99, 1999.

C. P. Valcke, H. J. Chizeck, “Closed-loop drug delivery for control of heart rate trajectory in pharmacological stress testing”, IEEE Trans Biomed Eng, pg. 185-195, March 1997.

M. Young, C. Valcke, K. Mullane, P. Gardiner, “Arbutamine: A Novel Catecholamine for Pharmacologic Diagnosis of Coronary Disease”, Cardiovasc Drug Reviews, Vol. 13, No. 4, pg. 379-398, 1995.

C. P. Valcke, J. S. Jenkins, D. S. Ward, “Recursive identification of lung parameters”, Computer Methods and Programs in Biomedicine, Vol. 29, pg. 143-149, 1989.

J. S. Jenkins, C. P. Valcke, and D. S. Ward, “An extended soluble gas exchange model for estimating pulmonary perfusion. I: Derivation and implementation”, IEEE Trans Biomed Eng (part1), Vol. 36, No. 11, pg. 1098-1104, 1989

C. P. Valcke, J. S. Jenkins, and D. S. Ward, “Modeling and estimation of lung parameters”, Bioinstrumentation and Biosensors, Ed: L. Wise, Marcel Dekker, New York 1991